MSTM is developing a high throughput multi-ionization vacuum ionization source capable of vauum MALDI (1 sample/sec) and vacuum MAI (1 sample/3 sec) with high sensitivity. The attached video shows the simplicity of obtaining mass spectra from a single sample of ubiquitin in a undiluted detergent solution using 3-NBN as the vMAI matrix. Once the sample plate is loaded onto the guiderail, multiple samples can be acquired by simply sliding the multisample plate over the channel to the vacuum of the mass spectrometer. Ionization spontaneously occurs when the sample experiences the vacuum of the mass spectrometer. In the video, we show loading, acquiring, and unloading the sample in ca. 10 sec.

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MS™ Solutions, LLC, is a company supported by an NSF Phase II award to develop advanced ionization technologies. We offer a platform for matrix-assisted ionization (MAI), solvent-assisted ionization (SAI), voltage-assisted SAI, electrospray ionization (ESI), and we sell atmospheric pressure solids analysis probe (ASAP) kits. ESI/MAI/SAI automation coming soon!


This material is based upon work supported by the National Science Foundation under Grant No. 1556043. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s), and do not necessarily reflect the views of the National Science Foundation. MAI, SAI, and vSAI are protected under US patent 2013/0214154 (A1) and ASAP(R) under US patent 2011/003139(A1). ASAP is a registered trademark of M&M Mass Spec Consulting, LLC.